Fluid bed granulation is a unique technique used for the blending of mixed powders and liquids. This is done with the help of a machine called fluid bed granulator. Its working principle is to pass hot air over the mixture of powders and liquids. The hot air lifts the particles and keeps them suspended, like it was in the air. The process to achieve this is termed fluidization. The particles shuffle about and collide with one another, fusing together. This allows them to coalesce into larger particles, very important in pharmaceuticals and also food products.
Fluid bed granulation, one of the biggest advantages is particle size & weight control. This control is critical since various sizes of particles can alter the efficacy of a medicine within our bodies. Smaller particles dissolve rapidly; bigger ones take more time. Controlling the size of such particles is vital, as this enables manufacturers to produce a medicine that is safe and effective for an intended population group.
Fluid bed granulation also has quicker and more efficient process than other manufacturing methods which help to retain all these properties aside from controlling particle size. Because it uses a fluidized bed to mix and coat the powders as well as liquids, processing times can be reduced without additional machines or steps. This can save a lot of time and money, which is crucial to organizations needing large-scale rapid manufacture of therapeutic goods.
IntroductionFluid bed granulation has been used in the pharmaceutical industry from a long span of time however, introduction to the food industry began relatively recently[1]. The reason behind this transition is, fluid bed granulation produces unique characteristics of the powders and granules. For instance, it might enhance a product's solubility (how well it dissolves in water) or improve its taste.
Fluid bed granulation is particularly beneficial in the food industry when it comes to instant drink mixes. These beverages are extremely popular as they can be prepared in seconds. In a very short time, it helps manufacturers in effectively blending various powders and liquids using the fluid bed granulator. This results in a reliable and high-quality product for folks to enjoy without any hassle.
Fluidization: The machine is switched on post the mixture loaded. Through the bed of powders/liquids the hot air is blown, and it gets to a fluidized state where everything moves. This ensures the equal mixture of the contents and acts as an assistant for coating it.
An area of development has also been made in functional granulators. These machines can carry out several various duties at the same time and reduces the necessity of numerous machines. This not only conserves space but also streamlines the entire process at the manufacturing facility.
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